{"id":3645,"date":"2025-07-09T22:21:52","date_gmt":"2025-07-09T14:21:52","guid":{"rendered":"https:\/\/glorichemical.com\/?post_type=product&p=3645"},"modified":"2025-12-07T10:25:53","modified_gmt":"2025-12-07T02:25:53","slug":"hydroxypropyl-beta-cyclodextrin-cas-128446-35-5","status":"publish","type":"product","link":"https:\/\/glorichemical.com\/ru\/product\/hydroxypropyl-beta-cyclodextrin-cas-128446-35-5\/","title":{"rendered":"HYDROXYPROPYL-BETA-CYCLODEXTRIN CAS 128446-35-5"},"content":{"rendered":"

1. What is Hydroxypropyl-beta-Cyclodextrin?<\/h2>\n

Hydroxypropyl-beta-Cyclodextrin (HP-\u03b2-CD) is a water-soluble derivative of beta-cyclodextrin, widely used as an inclusion complexing agent to enhance the solubility, stability, and bioavailability of poorly soluble substances. It is odorless, tasteless, and non-toxic, making it ideal for pharmaceutical, cosmetic, food, and chemical applications.<\/p>\n

2. Chemical Properties<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u041f\u0440\u0435\u0434\u043c\u0435\u0442\u044b \u0434\u043b\u044f \u0438\u0441\u043f\u044b\u0442\u0430\u043d\u0438\u0439<\/strong><\/th>\nChP 2020 Standard<\/strong><\/th>\nUSP-NF 2024 Standard<\/strong><\/th>\n<\/tr>\n<\/thead>\n
\u0412\u043d\u0435\u0448\u043d\u0438\u0439 \u0432\u0438\u0434<\/strong><\/td>\nWhite or almost white amorphous or crystalline powder. Very soluble in water or propylene glycol, soluble in methanol or ethanol, almost insoluble in acetone or chloroform.<\/td>\nWhite or almost white amorphous or crystalline powder; soluble in water and propylene glycol.<\/td>\n<\/tr>\n
Molar Substitution<\/strong><\/td>\nN\/A<\/td>\n0.4\u20131.5<\/td>\n<\/tr>\n
Solution Clarity and Color<\/strong><\/td>\nShould be clear and colorless<\/td>\n1.0g\/2ml aqueous solution is clear and transparent; remains transparent at room temperature<\/td>\n<\/tr>\n
\u0418\u0434\u0435\u043d\u0442\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u044f<\/strong><\/td>\nPurple ring appears at the interface of two liquids<\/td>\nInfrared absorption spectrum complies with standard (IR)<\/td>\n<\/tr>\n
pH<\/strong><\/td>\n5.0\u20137.5<\/td>\nN\/A<\/td>\n<\/tr>\n
\u0421\u043e\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u0435 \u0432\u043e\u0434\u044b<\/strong><\/td>\nNot more than 6.0%<\/td>\n\u226410.0%<\/td>\n<\/tr>\n
\u041f\u0440\u043e\u0432\u043e\u0434\u0438\u043c\u043e\u0441\u0442\u044c<\/strong><\/td>\nNot more than 200\u03bcS\/cm<\/td>\n\u2264200\u03bcS\/cm<\/td>\n<\/tr>\n
Epoxypropane (Propylene Oxide)<\/strong><\/td>\nNot more than 0.0001%<\/td>\n\u22641ppm<\/td>\n<\/tr>\n
1,2-Propylene Glycol<\/strong><\/td>\n\u041d\u0435 \u0431\u043e\u043b\u0435\u0435 0,5%<\/td>\n\u22642.5%<\/td>\n<\/tr>\n
Other Single Impurity<\/strong> (excluding Beta-Cyclodextrin and 1,2-Propylene Glycol)<\/td>\n\u041d\u0435 \u0431\u043e\u043b\u0435\u0435 0,1%<\/td>\n\u22640.25%<\/td>\n<\/tr>\n
Total Other Impurities<\/strong> (excluding Beta-Cyclodextrin and 1,2-Propylene Glycol)<\/td>\n\u041d\u0435 \u0431\u043e\u043b\u0435\u0435 1,0%<\/td>\n\u22641.0%<\/td>\n<\/tr>\n
\u0411\u0435\u0442\u0430-\u0446\u0438\u043a\u043b\u043e\u0434\u0435\u043a\u0441\u0442\u0440\u0438\u043d<\/strong><\/td>\n\u041d\u0435 \u0431\u043e\u043b\u0435\u0435 0,5%<\/td>\n\u22641.5%<\/td>\n<\/tr>\n
\u041e\u0441\u0442\u0430\u0442\u043a\u0438 \u043f\u0440\u0438 \u0432\u043e\u0441\u043f\u043b\u0430\u043c\u0435\u043d\u0435\u043d\u0438\u0438<\/strong><\/td>\n\u041d\u0435 \u0431\u043e\u043b\u0435\u0435 0,2%<\/td>\nN\/A<\/td>\n<\/tr>\n
\u0422\u044f\u0436\u0435\u043b\u044b\u0435 \u043c\u0435\u0442\u0430\u043b\u043b\u044b<\/strong><\/td>\nNot more than 10 ppm<\/td>\nN\/A<\/td>\n<\/tr>\n
\u0425\u043b\u043e\u0440\u0438\u0434<\/strong><\/td>\nNot more than 0.05%<\/td>\nN\/A<\/td>\n<\/tr>\n
Hydroxypropoxy Group Content<\/strong><\/td>\n19.6%\u201326.3%<\/td>\nN\/A<\/td>\n<\/tr>\n
Total Aerobic Microbial Count (cfu\/g)<\/strong><\/td>\nNot more than 100cfu\/g<\/td>\n\u22641000cfu\/g<\/td>\n<\/tr>\n
Total Yeasts and Molds (cfu\/g)<\/strong><\/td>\nNot more than 100cfu\/g<\/td>\n\u2264100cfu\/g<\/td>\n<\/tr>\n
\u041a\u0438\u0448\u0435\u0447\u043d\u0430\u044f \u043f\u0430\u043b\u043e\u0447\u043a\u0430<\/strong><\/td>\nAbsent in 10g<\/td>\nAbsent<\/td>\n<\/tr>\n
\u0421\u0430\u043b\u044c\u043c\u043e\u043d\u0435\u043b\u043b\u0430<\/strong><\/td>\nAbsent in 10g<\/td>\nAbsent<\/td>\n<\/tr>\n
Bacterial Endotoxins<\/strong><\/td>\nN\/A<\/td>\n\u226410EU\/g<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

3. Application<\/h2>\n

Hydroxypropyl-beta-Cyclodextrin is widely used in:<\/p>\n

    \n
  • \n

    Pharmaceuticals:<\/strong> To improve the solubility, bioavailability, and stability of active pharmaceutical ingredients (APIs).<\/p>\n<\/li>\n

  • \n

    Cosmetics:<\/strong> To stabilize volatile compounds, control odor release, and enhance product texture.<\/p>\n<\/li>\n

  • \n

    Food & Beverages:<\/strong> As a carrier for flavors, vitamins, and sensitive ingredients.<\/p>\n<\/li>\n<\/ul>\n

    \u00a0 \u00a0 \u00a0 \u00a0 \u00a0Chemical Industry:<\/strong> As an encapsulation agent for agrochemicals, fragrances, and functional materials.<\/p>\n

    \"HP-\u03b2-CD\"<\/p>\n

    4. Packing<\/h2>\n
      \n
    • \n

      1kg aluminum foil bag<\/p>\n<\/li>\n

    • \n

      10kg fiber drum<\/p>\n<\/li>\n

    • \n

      25kg fiber drum<\/p>\n<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"

      CAS : 128446-35-5
      Molecular Formula: C42H70O35
      Molecular Weight: 1135.00
      Appearance: White powder or granule
      Synonyms: HP-\u03b2-CD; Hydroxypropyl beta cyclodextrin; HPBCD<\/p>","protected":false},"featured_media":3646,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[21],"product_tag":[1386,1385,1384],"class_list":{"0":"post-3645","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-api","7":"product_tag-128446-35-5","8":"product_tag-cas-128446-35-5","9":"product_tag-hydroxypropyl-beta-cyclodextrin","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"yoast_head":"\nHYDROXYPROPYL-BETA-CYCLODEXTRIN CAS 128446-35-5<\/title>\n<meta name=\"description\" content=\"CAS 128446-35-5 Molecular Formula: C42H70O35 Molecular Weight: 1135.00Appearance: White powder or granuleSynonyms: HP-\u03b2-CD; Hydroxypropyl beta cyclodextrin; HPBCD\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/glorichemical.com\/ru\/product\/hydroxypropyl-beta-cyclodextrin-cas-128446-35-5\/\" \/>\n<meta property=\"og:locale\" content=\"ru_RU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HYDROXYPROPYL-BETA-CYCLODEXTRIN CAS 128446-35-5\" \/>\n<meta property=\"og:description\" content=\"CAS 128446-35-5 Molecular Formula: C42H70O35 Molecular Weight: 1135.00Appearance: White powder or granuleSynonyms: HP-\u03b2-CD; 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