Description
What is N-Bromosuccinimide CAS 128-08-5
N-Bromosuccinimide (NBS) is an important reagent in organic synthesis, a brominating and oxidising agent, mainly used in free radical reactions and electrophilic addition reactions. It is a good bromination reagent for the chemical raw materials commonly used in the industry, mainly used for regulating low-energy bromination reaction.
Chemical Properties
| Item | Standard |
| Appearance | White or pale yellow crystals |
| Assay | ≥99% |
| Active Bromine | ≥43% |
| InChIKey | PCLIMKBDDGJMGD-UHFFFAOYSA-N |
| LogP | -1.19 |
| Merck | 141,438 |
| Loss of drying | ≤0.5% |
Application
N-Bromosuccinimide (NBS) is a highly versatile compound in organic chemistry, and it has several important applications:
- Brominating Agent: NBS is an effective brominating agent. It selectively targets the α-H atoms attached to double bonds or benzene rings. This makes it invaluable for precise modifications.
- Catalyst: NBS also serves as a catalyst in some organic reactions. For instance, it is used in the synthesis of nitrogen-containing organic compounds from organic amines and olefins.
- Oxidizing Agent: NBS is a reliable oxidizing agent. Chemists commonly use NBS to oxidize secondary alcohols to ketones. This oxidation is a crucial step in many organic synthesis pathways.
- Raw Material in Organic Synthesis: NBS plays a significant role in commercial organic synthesis. For example, it is used to produce synthetic rubber additives and pharmaceuticals, such as cortisone and vitamin D3.
- Pesticide Industry: NBS widely uses in the pesticide industry. Moreover, it contributes to the synthesis of pesticides like thiram, which are essential for agricultural practices.
Packing
25kgs/drum, 9tons/20’container
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