Levofloxacin heMihydrate CAS 138199-71-0

This product is the L-body of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial DNA gyrase (bacterial topoisomerase I) and hinder bacterial DNA replication. This product has the characteristics of broad antibacterial spectrum and strong antibacterial effect. It is effective against most Enterobacteriaceae bacteria, such as Escherichia coli, Klebsiella spp., Serratia spp., Proteus spp., Shigella spp., and Salmonella spp. , Citrobacter, Acinetobacter, Pseudomonas aeruginosa, Haemophilus influenzae, Neisseria gonorrhoeae and other Gram-negative bacteria have strong antibacterial activity.

It also has good antibacterial effects on some methicillin-sensitive Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, hemolytic Streptococcus and other Gram-positive bacteria, as well as Legionella, Mycoplasma, Chlamydia, etc. But it has poor effect on anaerobic bacteria and enterococci.