Description
Diethyl Maleate CAS 141-05-9 Quick Details
| Chemical Name: | Diethyl Maleate |
| Other Name: | Diethylester kyseliny maleinove; Diethyl (2Z)-2-butenedioate |
| CAS: | 141-05-9 |
| EINECS: | 205-451-9 |
| Type: | Pharmaceutical intermediates; Organic raw materials |
| Molecular Formula: | C8H12O4 |
| Molecular Weight: | 172.18 |
Diethyl Maleate CAS 141-05-9 Chemical Properties
| Melting point | -10 °C (lit.) |
| Boiling point | 225 °C (lit.) |
| density | 1.064 g/mL at 25 °C (lit.) |
| vapor density | 5.93 (vs air) |
| vapor pressure | 1 mm Hg ( 14 °C) |
| refractive index | n20/D 1.441(lit.) |
| Fp | 200 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 14mg/l |
| form | Liquid |
| color | Clear |
| Odor | at 100.00 %. fruity banana citrus |
| Odor Type | fruity |
| Water Solubility | insoluble |
| Merck | 14,3123 |
| BRN | 1100825 |
| Dielectric constant | 8.6（23℃） |
| Stability: | Stable. Combustible. Incompatible with oxidizing agents, bases, acids, reducing agents. |
Diethyl Maleate Uses
1. Chemical Properties and Applications
Diethyl maleate serves as a solvent in gas chromatography with a stationary liquid that has a maximum use temperature of 40°C. Common solvents include benzene, chloroform, and ethanol. This compound functions as a solvent for resins and nitrocellulose, as well as a plasticizer in organic synthesis, pesticides, polymer monomers, and plastic additives.
2. Role in Pesticide Production
One of the primary applications of diethyl maleate is in producing the organophosphorus pesticide malathion. This compound acts as an intermediate in the synthesis of various pesticides, medicines, fragrances, and water stabilizers, particularly organic polycarboxylic acid phosphonic acid compounds.
3. Unsaturated Polyester Resin
Diethyl maleate is also an unsaturated polyester resin. It reinforces glass fibers used in ships, pipes, bathtubs, roof panels, and more. Additionally, it serves in protective coatings, topcoats, and varnishes.
4. Organic Synthesis
As a synthetic reagent, diethyl maleate aids in producing a variety of organic compounds, including polyaspartic acid ester-based polyurea coatings. Research indicates that it can inhibit the growth of MCA and TPA-transformed cells by regulating glutathione, mitogen-activated protein kinases, and cancer pathways.
5. Medical Uses
In the medical field, diethyl maleate primarily produces the insecticide malathion. It also acts as a chemical consumer of glutathione and has been widely studied for its impact on renal function. Other medical applications include treating breast cancer and monitoring the disease with positron emission tomography. Furthermore, the US Food and Drug Administration has approved it as a food additive for indirect contact with food.
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