2-Methylimidazole CAS 693-98-1

Description

2-MethylimidazoleQuick Details

Chemical Name: 2-Methylimidazole

Synonyms: 2-Methyl-1H-imidazole; 2-methyl-imidazol

CAS No.: 693-98-1

Molecular Formula: C4H6N2

Chemical Structure:

Molecular weight: 82.1

Appearance: White crystal power

Assay: 99%min

2-MethylimidazoleTypical Properties

2-methylimidazole synthesis method

Dehydrogenation Methods for 2-Methylimidazole Production

1. Dehydrogenation by Elimination of 2-Methylimidazoline:
   To synthesize 2-methylimidazole, 2-methylimidazoline is first heated and melted (melting point 107°C). Active nickel is carefully introduced into the mixture, and the temperature is raised to 200-210°C for 2 hours to initiate the dehydrogenation reaction. After the reaction is complete, the temperature is lowered to below 150°C. The mixture is then dissolved in water, hot-pressed, and the active nickel is separated. The filtrate is concentrated above 140°C, and upon cooling, 2-methylimidazole is obtained. This method yields a product with a purity of ≥98%. The process consumes 1095 kg of ethylenediamine (95%) and 975 kg of acetonitrile for every ton of product.
2. Glyoxal Method:
   Alternatively, glyoxal can be used as a raw material in a cyclization reaction with acetaldehyde and ammonia at approximately 45°C. The reaction proceeds through dehydration, followed by crystallization to isolate 2-methylimidazole. This glyoxal-based method has notable advantages, including the availability of raw materials, a shorter process route, lower production costs, and reduced environmental impact. Due to these benefits, the glyoxal method is widely adopted by manufacturers of 2-methylimidazole.

Applications of 2-Methylimidazole

1. Feed Additive:
   2-methylimidazole is used as a feed drug additive in pharmaceutical formulations.
2. Intermediate in Drug Production:
   This compound serves as an intermediate for producing the feed growth promoter dimethylazole, which is important in animal feed formulations.
3. Epoxy Resin Curing Agent:
   2-methylimidazole is utilized as a curing agent for epoxy resins and other types of resins. It is particularly effective as a medium-temperature solidifying agent for epoxy resin, where it can be used alone or primarily as a curing accelerator for powder molding and powder coating applications.
4. Dyeing Agent:
   Additionally, 2-methylimidazole can be employed as an adjuvant in the dyeing of fiber fabrics, enhancing color fastness and fabric quality.
5. Foam Additive:
   This compound is also used as an additive in the preparation of foam, improving the foam’s stability and texture.