Description
Tolfenamic acidQuick Details
Chemical Name:Tolfenamic acid
CAS: 13710-19-5
Molecular Fomula:C14H12ClNO2
Molecular Weight:261.7
Chemical Structure:
Appearance: White or slightly yellow, crystalline powder
Purity: 99.0~101.0%
Tolfenamic acidTypical Properties
Inspect Item | Specification | Results |
Appearance | White or slightly yellow, crystalline powder | Conforms |
Solubility | Practically insoluble in water, soluble in dimethylformamide, sparingly soluble in ethanol and in methylene chloride | Conforms |
Identification | A. Light absorption: the ratio of the absorbance measured at the maximum at 286nm to that maximum at 345nm should be 1.2 to 1.4 | Conforms |
B. IR absorption spectrophotometry should be conformed | 1.2 | |
C. TLC chromatography (245nm) should be conformed | Conforms | |
Melting point | 210~214℃ | 212.1~212.6℃ |
Related substances | Impurity A<0.1%;Impurity B<0.05% | Conforms |
Any other impurity<0.1% | Conforms | |
Total impurity<0.5% | Conforms | |
Copper | Not more than 10ppm | Conforms |
Loss on drying | Not more than 0.5% | 0.20% |
Sulphated ash | Not more than 0.1% | <0.1% |
Assay (basis on dry) | 99.0~101.0% | 99.70% |
Conclusion | The results conforms with EP6.0 standards |
Tolfenamic acid Usage
This product is used in the synthesis of non-steroidal anti-inflammatory analgesics.
Tolfenamic acid Packaging
25 kg/drum.
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