Carbocysteine CAS 2387-59-9

Carbocysteine is commonly used to treat non-suppurative otitis media in children and can help prevent deafness. As a respiratory mucus-dissolving agent, its function is similar to that of bromhexine. It works by breaking down the disulfide bonds in mucin, a component of sputum, which reduces its viscosity. This makes it easier for patients to cough up sputum. Additionally, carbocysteine increases the production of low-viscosity salivary mucin and decreases the production of high-viscosity fucomucin, further aiding in sputum clearance.

Mechanism and Clinical Uses

Carbocysteine functions as a mucus regulator at the cellular level, particularly targeting bronchial glands. By promoting the secretion of more fluid-like mucus and reducing thicker mucus, it helps relieve symptoms in conditions like chronic bronchitis and bronchial asthma. This action reduces airway blockages caused by thick sputum, making it easier to clear the airways.

In clinical applications, carbocysteine is used to manage patients with chronic respiratory conditions characterized by difficult-to-clear phlegm and excessive mucus production. Its ability to reduce sputum viscosity improves airway clearance, relieving symptoms and improving breathing.