توضیحات
Beta-Cyclodextrin CAS 7585-39-9 Quick Details
| Chemical Name: | Beta-Cyclodextrin |
| Other Name: | β-Cyclodextrin; Schardinger β-Dextrin; b-Cyclodextrin |
| CAS: | 7585-39-9 |
| EINECS: | 231-493-2 |
| Type: | Food additives; Pharmaceutical raw materials; Organic raw materials; Cosmetic raw materials |
| Molecular Formula: | C42H70O35 |
| Molecular Weight: | 1134.99 |
Chemical Properties
| Melting point | 290-300 °C (dec.) (lit.) |
| Boiling point | 844.96°C (rough estimate) |
| alpha | [α]D25 +159～+165° (c=1, H2O) (After Drying) |
| density | 1.2296 (rough estimate) |
| refractive index | 1.7500 (estimate) |
| storage temp. | room temp |
| solubility | 1 M NaOH: 50 mg/mL |
| form | powder |
| pka | 11.73±0.70(Predicted) |
| color | white |
| PH | 5.0-8.0 (1% in solution, Ph Eur) |
| optical activity | [α]20/D +162±3°, c = 1.5% in H2O |
| Water Solubility | Soluble in water and ammonium hydroxide. |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
Beta-Cyclodextrin Uses
Beta-Cyclodextrin (also known as cyclomaltose or β-CD) is derived from starch through microbial enzymes. Comprising seven sugar residues linked by β-1,4-glycosidic bonds, it forms a ring with a relative molecular weight of 1135. This unique structure allows it to interact with various compounds, providing benefits such as enhanced solubility, slow release, emulsification, and antioxidant properties.
Properties and Benefits
Beta-Cyclodextrin has several advantageous characteristics:
- High Selectivity: It can selectively encapsulate specific molecules.
- Non-Toxic and Edible: Safe for consumption.
- Non-Hygroscopic: Does not absorb moisture.
- Chemical Stability: Remains stable under various conditions.
- Easy Separation: Can be easily isolated from mixtures.
One notable application is its ability to absorb non-polar substances, like cholesterol, due to its internal diameter, which fits a single cholesterol molecule. This property allows β-CD to facilitate cholesterol removal from food products through centrifugation.
Applications in Various Industries
Food Industry
In food production, β-CD serves multiple purposes:
- Odor Removal: Effectively masks unwanted smells.
- Stabilization: Enhances the stability of spices, flavors, and pigments.
- Emulsification: Improves moisture-proofing capabilities.
- Flavor Enhancement: Acts as a stabilizer and flavoring agent.
Pharmaceutical Industry
In pharmaceuticals, β-CD is widely used to:
- Enhance Drug Stability: Prevents oxidation and degradation.
- Improve Dissolution and Bioavailability: Increases the effectiveness of medications.
- Reduce Side Effects: Minimizes toxicity and adverse reactions.
- Mask Odors: Conceals unpleasant smells in drugs.
Conclusion
Beta-Cyclodextrin is a versatile compound with significant applications in food and pharmaceutical industries. Its ability to enhance stability, solubility, and flavor makes it an invaluable ingredient in various formulations.
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