توضیحات
Acetyl Bromide CAS 506-96-7 Quick Details
| Chemical Name: | Acetyl Bromide |
| Other Name: | Acetylbrimide; CH3COBr; Ethanoylbromide |
| CAS: | 506-96-7 |
| EINECS: | 208-061-7 |
| Type: | Pharmaceutical raw materials; Organic raw materials; Pharmaceuticals, pesticides, dyes, synthetic material intermediates |
| Molecular Formula: | C2H3BrO |
| Molecular Weight: | 122.95 |
Chemical Properties：
| Melting point | -96 °C |
| Boiling point | 75-77 °C(lit.) |
| density | 1.663 g/mL at 25 °C(lit.) |
| vapor density | 4.3 (vs air) |
| vapor pressure | 92.2 mm Hg ( 25 °C) |
| refractive index | n20/D 1.45(lit.) |
| Fp | >230 °F |
| storage temp. | Store at <= 20°C. |
| solubility | Miscible with ether, chloroform, benzene and acetone. |
| form | Fuming Liquid |
| color | Clear colorless to dark yellow |
| Odor | Acrid and sharp. |
| Water Solubility | REACTS |
| Sensitive | Moisture Sensitive |
What is Acetyl Bromide?
Acetyl bromide is a colorless fuming fluid with a pungent smell, flammable, as well as turns yellow when revealed to the air. It is used as an acetylating agent in the synthesis of fine chemicals, agricultural chemicals as well as medications. It is likewise made use of as an intermediate of dyes. Acetylation is an instance of acylation, a natural synthesis procedure in which the acetyl group is bound to the molecule by changing the protective– OH group.
Acetyl bromide is an acyl bromide substance. As anticipated, it can be prepared by the reaction in between phosphorus tribromide as well as acetic acid:
3 CH 3 COOH + PBr 3 → 3 CH 3 COBr + H 3 PO 3
Like acyl halides, acetyl bromide hydrolyzes rapidly in water to form acetic acid and also hydrobromic acid. It also reacts with alcohol and amine to create acetate as well as acetamide, respectively.
Acetyl Bromide Uses
Acetyl bromide is made use of as an acetylating agent in the synthesis of fine chemicals, agricultural chemicals and also drugs. It is also used as an intermediate of dyes. In addition, it responds with alcohol as well as amine to create acetate and also acetamide. In addition, it is likewise associated with the synthesis of anti HIV medicines.
Acetyl bromide can be used for:
- Quantitative determination of lignin in cell wall residue of Arabidopsis thaliana.
- In total synthesis, cinchona alkaloids are named quinidine and quinine.
- The reaction of ZnBr2/SiO2 with aromatic hydrocarbons and various aromatic aldehydes was used to prepare 9,10-diarylanthracene and triarylmethane.
- Sugar bromide is prepared from free sugar or its peracetate.
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