بايونيفلورين CAS 23180-57-6 في دائرة المستخلصات الكيميائية

Paeoniflorin Overview

بايونيفلورين is the main active compound found in the dried root of the peony plant (Paeonia). Traditionally used in Chinese medicine, paeoniflorin has garnered attention for its diverse pharmacological properties.

Composition and Properties

• Chemical Formula: C23H28O11
• المظهر: White amorphous powder at room temperature
• الاستقرار: Sensitive to moisture, heat, acid, and alkali; prone to oxidation

التأثيرات الدوائية

Paeoniflorin exhibits a range of beneficial effects, including:

1. Anti-inflammatory: Reduces inflammation in various conditions.
2. Analgesic: Provides pain relief, making it useful for headaches and muscle cramps.
3. Neuroprotective: Offers protection against neurodegenerative diseases such as Alzheimer’s and Parkinson’s by counteracting oxidative stress and inhibiting astrocyte activation.
4. Liver Protection: Helps maintain liver health and may have protective effects against liver damage.
5. Immunomodulatory: Regulates immune responses, beneficial for autoimmune conditions like rheumatoid arthritis.

Traditional Uses

In traditional Chinese medicine, peony and its active component, paeoniflorin, are used to:

• Calm the liver and relieve pain
• Nourish blood and regulate menstruation
• Treat various symptoms like abdominal pain, dizziness, and night sweats

التطبيقات السريرية

Research suggests potential applications in:

• Cardiovascular Health: Used for conditions like coronary heart disease and myocardial ischemia.
• Metabolic Disorders: Shown to lower blood sugar levels, aiding in diabetes management.
• Respiratory Conditions: Acts as an adjunct therapy for chronic respiratory diseases, particularly in the elderly.

الخاتمة

Paeoniflorin is a versatile compound with significant therapeutic potential, particularly in traditional and modern medicine. Its anti-inflammatory, analgesic, and neuroprotective properties highlight its importance as a natural remedy in treating various health conditions.