الوصف
Oxaliplatin CAS 61825-94-3 Quick Details
| الاسم الكيميائي: | Oxaliplatin |
| اسم آخر: | Trans-l-diaminocyclohexane oxalatoplatinum; Eloxatin; Oxaliplatin and capecitabine |
| CAS: | 61825-94-3 |
| EINECS: | 621-248-1 |
| النوع: | Pharmaceutical raw materials; Pharmaceutical, agriculture, dye intermediates |
| الصيغة الجزيئية: | C8H12N2O4Pt |
| الوزن الجزيئي: | 395.28 |
Oxaliplatin CAS 61825-94-3 Chemical Properties
| ألفا | +74.5-78.0 (D/20)(c=0.5,H2O) |
| درجة حرارة التخزين. | 2-8°C |
| قابلية الذوبان | Slightly soluble in water, very slightly soluble in methanol, practically insoluble in anhydrous ethanol. |
| النموذج | solid |
| قابلية الذوبان في الماء | Soluble in water with heating and/or sonication |
| الاستقرار: | Stable. Store cool. Incompatible with oxidizing agents. |
Oxaliplatin Uses
- The third generation platinum complex. An anti-tumor representative with anti-colorectal cancer task. Cytotoxicity follows the formation of DNA adducts. Antitumor.
- Oxaliplatin is a platinum-based antineoplastic drug that works by specifically creating DNA adducts in cancer cells, protecting against DNA replication as well as transcription that lead to cell death.
- Oxaliplatin is cytotoxic in numerous cell lines consisting of colon, ovarian and also lung cancer cells with IC50 values of 0.5-240, 0.12-19.8 as well as 2.6-6.1 μM, respectively.
- Via its general cytotoxic results, oxaliplatin has antitumor task versus advanced intestines cancer cells, normally in combination with fluorouracil as well as leucovorin, referred to as FOLFOX.
المراجعات
لا توجد مراجعات بعد.